PMSP-affiliated Publications

Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch J, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, Koboldt DC, Schmidt H, Zhang Q, Osborne JR, Lin L, O’Laughlin M, McMichael JF, Delehaunty KD, McGrath SD, Fulton LA, Magrini VJ, Vickery TL, Hundal J, Cook LL, Conyers JJ, Swift GW, Reed JP, Alldredge PA, Wylie T, Walker J, Kalicki J, Watson MA, Heath S, Shannon WD, Varghese N, Nagarajan R, Westervelt P, Tomasson MH, Link DC, Graubert TA, DiPersio JF, Mardis ER, Wilson RK. DNMT3A Mutations in Patients with Acute Myeloid Leukemia. N Engl J Med  2010: 363, 2424-2433. PMID: 21067377, PMCID: PMC3201818

Perrin RJ, Craig-Schapiro R, Malone JP, Shah AR, Gilmore P, Davis AE, Roe CM, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, Kaye JA, Morris JC, Holtzman DM, Townsend RR, Fagan AM. Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease. PLoS One 2011: 6(1): e16032. PMID 21264269, PMCID: PMC3020224

Chen ZW, Fuchs K, Sieghart W, Townsend RR, Evers AS.  Deep amino acid sequencing of native brain GABAA receptors using high-resolution mass spectrometry.  Mol Cell Proteomics 2012: 11(1): M111.011445.  PMID: 22338125, PMCID: PMC3270104

Morales DM, Townsend RR, Malone JP, Ewersmann CA, Macy EM, Inder TE, Limbrick DD Jr.  Alterations in protein regulators of neurodevelopment in the cerebrospinal fluid of infants with posthemorrhagic hydrocephalus of prematurity.  Mol Cell Proteomics 2012: 11(6): M111.011973. PMID: 22186713

Tiriveedhi V, Conzen KD, Liaw-Conlin J, Upadhya G, Malone JP, Townsend RR, Kerns R, Jia J, Csontos K, Ramachandran S, Mohanakumar T, Anderson CD Chapman WC, The role of molecular chaperonins in warm ischemia and reperfusion injury in the steatotic liver: A proteomics study. BMC Biochem 2012: 13, 17. PMID: 22962947

Marionneau C, Lichti CF, Lindenbaum P, Charpentier F, Nerbonne JM, Townsend RR, Mérot J, Mass spectrometry-based identification of native cardiac Nav1.5 channel α subunit phosphorylation sites. J Proteome Res 2012. PMID: 23092124

Klco JM, Spencer DH, Lamprecht TL, Wylie T, Magrini VJ, Hundal J, Walker J, Varghese N, Gilmore P, Lichti CF, Meyer MR, Townsend RR, Wilson RK, Mardis ER and Ley TJ, Genomic impact of transient low-dose decitabine treatment on primary AML cells. Blood 2012, in press.

Andley UP, Malone JP, Hamilton PD, Ravi N, Townsend RR. Comparative proteomic analysis identifies age-dependent increases in the abundance of specific proteins after deletion of the small heat shock proteins αA- and αB-crystallin. Biochemistry. 2013: 52(17):2933-48. PMCID: PMC3690595

Yip GM, Chen ZW, Edge CJ, Smith EH, Dickinson R, Hohenester E, Townsend RR, Fuchs K, Sieghart W, Evers AS, Franks NP. A propofol binding site on mammalian GABAA receptors identified by photolabeling. Nat Chem Biol. 2013; 9(11):715-20. PMCID: PMC3951778

Zhang B, Wang J, Wang X, Zhu J, Liu Q, Shi Z, Chambers MC, Zimmerman LJ, Shaddox KF, Kim S, Davies SR, Wang S, Wang P, Kinsinger CR, Rivers RC, Rodriguez H, Townsend RR, Ellis MJ, Carr SA, Tabb DL, Coffey RJ, Slebos RJ, Liebler DC; NCI CPTAC. Proteogenomic characterization of human colon and rectal cancer. Nature. 2014: 513(7518):382-7. PMCID: PMC4249766

Whiteaker JR, Halusa GN, Hoofnagle AN, Sharma V, MacLean B, Yan P, Wrobel JA, Kennedy J, Mani DR, Zimmerman LJ, Meyer MR, Mesri M, Rodriguez H; Clinical Proteomic Tumor Analysis Consortium (CPTAC), Paulovich AG. CPTAC Assay Portal: a repository of targeted proteomic assays. Nat Methods. 2014 Jul;11(7):703-4. PMCID: PMC4113142

McNulty SN, Rosa BA, Fischer PU, Rumsey JM, Erdmann-Gilmore P, Curtis KC, Specht S, Townsend RR, Weil GJ, Mitreva M. An Integrated Multiomics Approach to Identify Candidate Antigens for Serodiagnosis of Human Onchocerciasis. Mol Cell Proteomics. 2015 Dec;14(12):3224-33. doi: 10.1074/mcp.M115.051953. Epub 2015 Oct 15. PMID: 26472727 [PubMed - in process]

Mertins P, Mani DR, Ruggles KV, Gillette MA, Clauser KR, Wang P, Wang X, Qiao JW, Cao S, Petralia F, Kawaler E, Mundt F, Krug K, Tu Z, Lei JT, Gatza ML, Wilkerson M, Perou CM, Yellapantula V, Huang KL, Lin C, McLellan MD, Yan P, Davies SR, Townsend RR, Skates SJ, Wang J, Zhang B, Kinsinger CR, Mesri M, Rodriguez H, Ding L, Paulovich AG, Fenyö D, Ellis MJ, Carr SA; NCI CPTAC. Proteogenomics connects somatic mutations to signalling in breast cancer. Nature. 2016 May 25;534(7605):55-62. doi: 10.1038/nature18003. PMID: 27251275 [PubMed - indexed for MEDLINE]

Zhang H, Liu T, Zhang Z, Payne SH, Zhang B, McDermott JE, Zhou JY, Petyuk VA, Chen L, Ray D, Sun S, Yang F, Chen L, Wang J, Shah P, Cha SW, Aiyetan P, Woo S, Tian Y, Gritsenko MA, Clauss TR, Choi C, Monroe ME, Thomas S, Nie S, Wu C, Moore RJ, Yu KH, Tabb DL, Fenyö D, Bafna V, Wang Y, Rodriguez H, Boja ES, Hiltke T, Rivers RC, Sokoll L, Zhu H, Shih IM, Cope L, Pandey A, Zhang B, Snyder MP, Levine DA, Smith RD, Chan DW, Rodland KD; CPTAC Investigators. Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer. Cell. 2016 Jun 28. pii: S0092-8674(16)30673-0. doi: 10.1016/j.cell.2016.05.069. [Epub ahead of print]. PMID: 27372738 [PubMed - as supplied by publisher]