Judith A. Aberg\, MD\, FIDSA\, FACP
Dr.
George Baehr Professor of Medicine
Dean of System Operations for Clin
ical Sciences
System Chief\, Infectious Diseases
Icahn School of
Medicine at Mount Sinai
Aberg is the Dean of System Operations for Cl inical Sciences\, System Chief of Infectious Diseases\, and Dr. George Baeh r Professor of Medicine at the Icahn School of Medicine at Mount Sinai. An internationally renowned expert in infectious disease and clinical trials\, she also serves as a Dean working with others to introduce and integrate c linical and translational research across the Mount Sinai Health System. Ab erg was an integral part of Mount Sinai’s COVID-19 response\, from introduc ing antiviral and immunomodulating therapies to opening vaccine studies. Sh e has been involved in more than 200 clinical trials and currently serves a s a member of the NIH COVID-19 Treatment Guidelines panel.
<
strong>Charles P. Friedman\, PhD
Josiah Macy Jr. Professo
r of Medical Education
Chair\, Department of Learning Health Sciences<
br />University of Michigan Medical School
Friedman is the Josiah Mac y Jr. Professor of Medical Education and Chair of the Department of Learnin g Health Sciences at the University of Michigan Medical School. His academi c interests focus on the concept of Learning Health Systems that improve he alth by marrying discovery to implementation\, and the socio-technical infr astructure required to sustain these systems. He is editor-in-chief of the open-access journal Learning Health Systems and co-chair of the global move ment to Mobilize Computable Biomedical Knowledge. Prior roles include execu tive positions at the Office of the National Coordinator for Health IT (ONC ) in the U.S. Department of Health and Human Services and Associate Vice Ch ancellor for Biomedical Informatics and Founding Director of the Center for Biomedical Informatics at the University of Pittsburgh.
Bettina Drake\, PhD\, MPH
Professor of
Surgery
Associate Director of Community Outreach and Engagement
Siteman Cancer Center
Washington University School of Medicine in St.
Louis
Drake is Professor in the Division of Public Health Sciences a t Washington University School of Medicine and Associate Director of Commun ity Outreach and Engagement for the Alvin J. Siteman Cancer Center. Her res earch focuses on identifying preventive strategies and integrating communit y engagement approaches to reduce cancer disparities. The objectives of her research program are: to utilize community-based approaches to design\, im plement and disseminate research information\; to promote education and awa reness of research participation in minority communities\; and to identify the modifiable and non-modifiable risk factors for cancer and other chronic diseases as well as the at-risk groups for these factors.
Clay Dunagan
\, MD\, MS
Professor of Medicine
Washington Universi
ty School of Medicine in St. Louis
Dunagan is Professor of Medicine w ith an appointment in the Division of Infectious Diseases. He served as a c orporate officer and clinical leader for BJC HealthCare where he served as the vice president for quality from 1994 until 2015 and as senior vice-pres ident and chief clinical officer from 2015 to 2023. Dungan worked collabora tively with Washington University Physicians in overseeing the development of evidence-based approaches to care\, including the meaningful use of heal th information technology to support care\; strategies to improve care inte gration across the continuum of services offered by the health system\; and accountability measures for outcomes at the individual clinician\, hospita l and system levels.
Christina Gurnett\, MD\, PhD
A. Ernest and Jane G. Stein Professor of Developmental Neurology
Professor of Neurology\, Pediatrics
Associate Director\, Institute
of Clinical and Translational Sciences
Director\, Division of Pediatri
c and Developmental Neurology
Neurologist-in-Chief\, St. Louis Childre
n’s Hospital
Washington University School of Medicine in St. Louis
Gurnett is a physician-scientist who is the Co-Director of the Washingto n University Intellectual and Developmental Disabilities Research Center. S he completed her MD and PhD degrees at the University of Iowa and came to W ashington University School of Medicine in 2000 for neurology residency and a clinical neurophysiology fellowship. Since 2014\, she has co-directed th e precision medicine pathway for graduate students. She has an active resea rch laboratory whose goals include gene discovery for musculoskeletal disor ders and the development of high throughput methods to improve variant inte rpretation. She is also the co-PI for two RADx-UP Return to School testing projects for COVID-19.
Thomas Kannampallil\, PhD
Associate Professor of An
esthesiology
Faculty\, Institute for Informatics\, Data Science and Bi
ostatistics (I2DB)
Associate Chief Research Information Off
icer
Washington University School of Medicine in St. Louis
Kanna mpallil is an Associate Professor of Anesthesiology and the Associate Chief Research Information Officer at Washington University School of Medicine. His research interests lie at the intersection of computer science\, cognit ive science\, and clinical informatics. His research focuses on developing and evaluating intelligent computational tools for improving clinical decis ion making and patient safety. He currently serves on ONC and PCORI technic al expert panels on health information technology. His research is funded b y R01s from the National Library of Medicine\, National Institute of Aging\ , and the Agency for Healthcare Research and Quality. He was elected as a F ellow of the American Medical Informatics Association in 2021.
Ginge
r Nicol\, MD
Associate Professor of Psychiatry
Direc
tor\, Child and Adolescent Psychiatry Residency Research Education Program<
br />Director\, Mobile Health Research Core
Washington University Scho
ol of Medicine in St. Louis
Nicol is an Associate Professor of Psychi atry at Washington University School of Medicine where she and her team in the Healthy Mind Lab employ precision methods such as digital and genetic p henotyping\, PET imaging and functional MRI to better understand how medica l and behavioral treatments work to optimize human mental and physical heal th. She directs the Mobile Health Research Core\, part of the WUSM Institut e of Clinical and Translational Sciences and co-directs the Psychiatry Resi dency Research Education Program. She is a Certified Eating Disorder Specia list and is board certified in Obesity Medicine.
Philip R. O. Payne\, PhD\, FACMI\, FAMIA\, FAIMBE\, FIAHSIJanet and Bernard Becker Professor and Director\, Institute for Informa
tics\, Data Science and Biostatistics (I2DB)
Associate Dean
for Health Information and Data Science
Chief Data Scientist\, School
of Medicine
Professor of Medicine\, Computer Science and Engineering
Washington University in St. Louis
Payne is the author of over 230 pu blications\, and his research\, innovation\, and workforce development expe rience spans a broad spectrum\, including: 1) machine learning and cognitiv e computing approaches to the discovery and analysis of bio-molecular and c linical phenotypes\; 2) interventional approaches to the use of electronic health records and clinical decision support systems\; 3) human factors and workflow issues surrounding the optimal use of healthcare information tech nology\; and 4) the design and evaluation of data sharing and analytics pla tforms that enable the operation of agile\, high-value healthcare delivery systems and research enterprises. Payne has a substantial track record of e ntrepreneurship\, having launched and led numerous start-up and spin-off co mpanies focusing on the broad digital health domain.
David H. Perlmutter\, MD
Executive Vice Chancellor for Medical Affairs
George an
d Carol Bauer Dean\, School of Medicine
Spencer T. and Ann W. Olin Dis
tinguished Professor
Washington University School of Medicine in St. L
ouis
Perlmutter is internationally recognized for his research on alp ha-1 antitrypsin deficiency\, a genetic disorder in which accumulations of a misfolded protein can cause severe liver damage. His work has led to adva nces in the understanding of how cells dispose of misfolded proteins that c ause cellular dysfunction. Perlmutter has been on the faculties of Harvard Medical School\, University of Pittsburgh and Washington University. Prior to his current position\, he was distinguished professor and chair of the D epartment of Pediatrics at University of Pittsburgh as well as physician-in -chief and scientific director of the Children’s Hospital of Pittsburgh of the University of Pittsburgh Medical Center.
William Powderly\, MD
J. William Campbell Professor of M
edicine
Associate Dean for Clinical and Translational Sciences
Di
rector\, Institute of Clinical and Translational Sciences
Larry J. Sha
piro Director\, Institute for Public Health
Co-Director of the Divisio
n of Infectious Diseases
Washington University School of Medicine in S
t. Louis
Powderly is currently director of the Washington University Institute for Public Health\, director of the Institute of Clinical and Tra nslational Sciences\, and co-director of the Division of Infectious Disease s. He has been actively involved in HIV-related clinical research for thirt y years. He has been a member of numerous advisory groups on HIV and infect ious diseases for the NIH\, the CDC\, the Canadian Institute for Health Res earch\, and the European Medicines Agency. His major recent focus is transl ating scientific advances to a wider population to improve public health.
Nancy Sweitzer\, MD\, PhD
Professor of MedicineVice-Chair of Medicine for Clinical Research
Associate Director\,
Institute of Clinical and Translational Sciences
Washington University
School of Medicine in St. Louis
Sweitzer is an advanced heart failur e and transplant cardiologist recognized for clinical trials leadership. Sh e has done extensive work on heart failure with preserved systolic function \, a disease that affects older women disproportionately. Before joining th e faculty at WashU\, she was director of the University of Arizona Sarver H eart Center and chief of cardiology in Tucson. She recently completed a ter m as chair of the NHLBI Clinical Trials Study Section. Sweitzer earned her undergraduate degree at Penn\, her MD at UW-Madison\, and trained at Brigha m and Women’s Hospital.
Yi Zhang
\, RN\, JD
Assistant Dean for Clinical Research
Administ
rative Director\, Center for Clinical Studies
Operations Officer\, Cli
nical and Translational Research Unit
Director\, Clinical Research in
Oncology
Washington University School of Medicine in St. Louis
Z hang has expertise in clinical research\, and operational\, regulatory\, le gal\, ethical and practical issues faced by clinical research investigators and staff. She has served the ICTS in different capacities across several domains and cores. Currently\, she serves as the operations officer for the Clinical and Translational Research Unit and the co-director of the Regula tory Knowledge and Support Center\, as well as playing a major role in the ICTS’ Network Capacity component.
| 8:30 am | Attendee check-in |
| 9:00-9:25 am | Welcome by ICTS Director William Powderly\,
MD School of Medicine Remarks by Dean David Perlmutter\, MD
Dr. Powderl y will highlight ICTS achievements and discuss future initiatives as the IC TS embarks upon its 16th year of consecutive funding from the Na tional Center for Advancing Translational Sciences. Winners of the poster c ompetition will be announced. |
| 9:25-10:00 am | Introd
uction by Philip Payne\, PhD Charles Friedman\, PhD “Socio-Technical Infrastructure for Learning Health Systems” One of three key defining features of a Learning Health System is i nfrastructure which serves the needs of all system activities to improve th e health of individuals and populations. The infrastructure can be thought of as a set of services comprised of people\, processes\, policies\, and te chnologies. Dr. Friedman will describe such an infrastructure and the speci fic services that comprise it. |
| 10:00-10:45 am | Q&A
and Panel with Dr. Friedman Clay Dunagan\, MD\, MS\; Thomas Kannampal lil\, PhD\; Nancy Sweitzer\, MD\, PhD Moderated by Christina Gurnett\ , MD\, PhD |
| 10:45-10:55 am | Break |
| 1 0:55-11:30 am | Introduction by William Powderly\, MD Judith Ab erg\, MD “Operationalizing Clinical Trials in Health Syst ems” Dr. Aberg will discuss how to operationalize and f acilitate the conduct of clinical trials across a health system\, including advantages of centralizing certain processes\, barriers to implementation\ , and thoughts of solutions. Lessons learned from the Mount Sinai experienc e will be highlighted. |
| 11:30 am-12:30 pm | Q&A and P
anel with Dr. Aberg Bettina Drake\, PhD\, MPH\; Ginger Nicol\, MD\; Y i Zhang\, RN\, JD Moderated by William Powderly\, MD |
| 12:30-1:00 pm | Boxed lunches available. Poster award recipients ava ilable with their posters in lobby. |
