David T. Monks, MD, MSC

Assistant Professor in Anesthesiology

Washington University in St. Louis (WU)

My principle area of research is in obstetric anesthesiology and specifically in improving the peripartum care of parturients delivering their babies by cesarean delivery. My publications so far have included a randomised controlled trial of gabapentin to improve post-cesarean analgesia and I have a review article examining the evidence in this regard currently under peer review. My current focus is on reducing postpartum hemorrhage (PPH). I plan to perform a series of studies to fully elucidate the pharmacokinetic and pharmacodynamic (PK/PD) profile of oxytocin, the most widely-used uterotonic agent in obstetric practice. There is a paucity of PK/PD data for oxytocin in the context of cesarean delivery and current dosing strategies pay no attention to individual patient factors and use inaccurate measures of clinical effect. The information that these studies will provide will improve our ability to optimise the dose in individual patients in order to reduce PPH.