Clinical and Translational Imaging Unit (CTIU)

Provides advanced imaging technology, equipment, and expertise to support basic and translational inpatient and outpatient clinical research.

The Clinical & Translational Imaging Unit (CTIU) – a component of the Clinical Research Nucleus (CRN) – consists of three Research Imaging Facilities in the Department of Radiology – the Center for Clinical Imaging Research (CCIR), the Radiology Clinical Research Core (RadCore), and the Cyclotron Facility. The Unit also includes a 3D Printing Lab which provides access to four printers and engineering support to construct 3D printed models from imaging data for pre-procedural planning, novel implant and device development, and for making small pieces of equipment for research studies.

The CCIR is a state-of-the-art biomedical imaging facility located on the 10th floor of the West Pavilion of Barnes-Jewish Hospital in St. Louis, MO. The CCIR provides the latest in advanced imaging technology, equipment and expertise to support basic and translational inpatient and outpatient clinical research.

RadCore provides coordination and project management services to support the basic and clinical research of Washington University investigators. RadCore assists in the training, design, execution, financial management and analysis of basic and clinical research.

The Mallinckrodt Institute of Radiology (MIR) at the Washington University School of Medicine (WUSM) Cyclotron Facility and Nuclear Pharmacy provides positron emission tomography (PET) isotopes, radiochemicals, radiotracers and radiopharmaceuticals to the research and medical communities. Used for research and clinical practice, these agents meet or exceed user requirements, while safely and reliably insuring the highest level of quality that is achievable within federal regulations and guidelines.


Services & Resources

CTIU provides a full range of biomedical imaging, study coordination, and radiopharmaceutical services

These services include:

  • Pre-study services that help investigators design, set up, and begin the study
  • Coordinating Services, including Scanning Services, that provide assistance in executing, monitoring and evaluating the study
  • Information Technology management services to manage, track, and process imaging data
CCIR Facilities
  • Subject waiting area
  • Two consultation rooms
  • Nurses’ workstation
  • Locked supply storage area
  • Temporary storage area
  • Refrigerator
  • Lab resources (not including supplies)
  • Wireless capability for laptops
  • Conference room
  • Technical expert staff for consultation and protocol integration
  • Assistance from nurses, coordinators and technologists
  • HPLC
  • Blood Sampler
  • Gamma Counter
  • Small Centrifuges
  • Hot labs
RadCore Services
  • Grant/protocol development
  • IRB/FDA Preparation, Submission, and Management
  • Budget Preparation and Negotiations
  • Contract Execution
  • Protocol Training and Study Start Up
  • Subject Recruitment and Enrollment
  • Study Coordination and Data Collection
  • Image Processing and Uploading
  • Study Termination
Cyclotron Facilities
  • Radiopharmaceuticals: Portfolio of over 20 human-use radiopharmaceuticals
  • Radiopharmaceutical development: Translation from bench to human use
  • Pharmacy services: Aseptic training, RDRC submission and writing of INDs, etc
3D Printing Lab
  • Fuse Deposition Modeling (FDM): Makerbot 2nd and 5th Generations
  • Bioprinting: Hyrel System 30M
  • Stereolithography: Formlabs Form2
  • Materials: Form2 compatible resins, flexible filaments, hydrogels
  • 3-D Medical Modeling: Computer visualization or physical models
  • Customized implants and surgical guides
Personnel Support

The CTIU has access to personnel with a wide range of expertise. The RadCore has 5 Sr. Clinical Research Coordinators, a Regulatory Specialist, and a Billing and Data Specialist. In addition, the CCIR has established a formal master research agreement with Siemens Medical which provides full-time, on-site personnel that work with WUSM to promote the development of new biomedical imaging technologies. The Cyclotron Facility provides a dedicated staff of scientists and pharmacists to ensure that both standardized and research offerings are handled with little need of outside assistance. The Cyclotron Facility can also help to develop new product offerings along with oversight into the regulatory requirements for these new products.

These groups work together to provide services, support, maintenance, and development needs for the Center.

Request a Service

The forms required to plan, develop and execute a research study in the CCIR may be downloaded from the CCIR Forms webpage.

Contact

Center for Clinical Imaging Research
See our program website for more detailed information.

Location

Center for Clinical Imaging Research (CCIR)
Mallinckrodt Institute of Radiology
510 S. Kingshighway, 10300 West Pavilion
Campus Box 8131
St. Louis, MO 63110-1093
Phone: 314-747-2300
Email: ccir@wustl.edu

CTIU Team

Pamela Woodard, MD, Director

Hongyu An, PhD, Associate Director