Clinical and Translational Research Unit (CTRU)

Provides in-patient and out-patient clinical research units for research studies.

The Clinical and Translational Research Unit (CTRU) operates as an in-patient and out-patient clinical research unit that provides the following resources:

CTRU Services & Resources


  • 4 Private and 8 Semi-private beds
  • 7 Exam rooms
  • 5 Phlebotomy areas
  • 4 Infusion bays
  • Dedicated cardiovascular testing room
  • Dedicated exercise testing and training rooms
  • Temperature-controlled room
  • Sleep study room
  • Metabolic kitchen
  • Certified iv infusate prep room
  • Body composition analysis (DEXA)
  • Laboratory for sample processing and temporary storage
  • Indirect calorimetry for assessment of energy expenditure


The CTRU is staffed by Registered Nurses with AHA ACLS and IATA certification, Medical Assistants, Registered Dieticians, Diet techs, and DEXA technicians to assist investigators and study teams with clinical research protocol development and implementation.

In addition, ACRP-certified Clinical Research Nurse Coordinators and Research Patient Coordinators are available for hire through the Center for Clinical Studies (CCS). Please contact Teresa Arb at 314-747-1217 or in the CCS for more information.


Nursing Support:

  • Standard care and assistance with specialized procedures (e.g. arterial line maintenance, hyperinsulinemic-euglycemic clamp procedure, intravenous glucose tolerance test, muscle and adipose tissue biopsies, endoscopy, lumbar puncture, bronchoscopy, cardiovascular, neuromuscular, and exercise and physical function testing)

Body Composition Analysis by DEXA:

  • Total and regional fat mass
  • Total and regional fat-free mass
  • Intraabdominal fat mass
  • Bone mass and mineral density

Nutrition Services:

  • Standard and precision meals and diets (inpatient and packed-out meals)
  • Diet analyses
  • Nutrition education
Specialized Equipment

Neuromuscular, Exercise and Physical Function Testing and Training

  • Muscle strength (Biodex System 4 dynamometer, weight machines, free weights)
  • Endurance exercise (treadmills, cycle ergometers, elliptical machines)
  • VO2 peak testing (treadmill/cycle ergometer and metabolic cart/indirect calorimeter )
  • Cardiac stress testing
  • Global physical performance

Vascular Testing

  • Vascular compliance and arterial stiffness (SphygmoCor system)
  • Endothelial function (EndoPat 2000)
  • Carotid artery intima media thickness (ultrasound)

Sleep Studies

  • Compumedics Grael PSG/EEG with video monitoring
  • Alice PDx portable sleep diagnostic system


  • Phillips Epiq7

Energy Metabolism and Lifestyle Monitoring

  • Metabolic carts
  • Activity and sleep monitors
  • Smart scales
  • Continuous glucose monitoring

Brown Adipose Tissue Studies

  • Cold suit
Service Hours

24 hours/day, beginning at 6 am Monday until 7pm on Friday. If additional hours are needed, please contact the CTRU Nurse Manager, Lisa Menneke, RN at 314-362-8144 or

Request a Service

Send an email to to request information about services that are currently offered or download and submit the CTRU Application Form (doc). or

Submit a “CTRU Modification Form (doc)“, if applicable.

Service available to: All entities, including for-profit organizations. Priority given to ICTS members.



Samuel Klein, MD, Medical Director

Dominic Reeds, MD, Medical Director

Gordon Smith, PhD, CTRU Director

Lisa Menneke, RN, Nurse Supervisor


Center for Outpatient Health,
5th Floor, Suite 510

4901 Forest Park Ave.,
St. Louis, MO 63108