Biorepository and Biospecimen Resource (BBR)

Formerly known as the “Tissue Procurement Core”, the BBR provides a centralized resource to process, store, and utilize biospecimens for translational and biomedical research.

The Biorepository and Biospecimen Resource (BBR) is a shared resource supported by the Siteman Cancer Center

and provides research programs and researchers with a centralized resource to process, store and utilize biospecimens for translational cancer and non-cancer biomedical research.

The BBR occupies 5,000 sq ft of wet-lab space on the fifth floor of the BJC Institute of Health (BJCIH) and an additional 2,800 sq ft of space at an off-site facility that supports secure and monitored long-term biospecimen storage.

The BBR maintains an archive of patient-matched malignant, non-malignant fixed and frozen tissues and biofluids for pilot, IRB-approved, retrospective correlative science studies, can assist investigators in the prospective collection, processing and storage of biospecimens from participants enrolled on clinical studies, and facilitates the use of biospecimens and their derivatives for genomic, molecular, metabolomic, and other translational research.

Dedicated staff and facilities generate bio-fluid, tissue, nucleic acid, single cell/nuclei, exosome and histological derivatives from patient-derived specimens. Services to facilitate tissue-based translational research such as laser capture microdissection, along with pathology consultation and digital imaging resources, are also available.