Alex R. Carter, MD, PhD

Instructor in Neurology

Washington University in St. Louis (WU)

My interests lie within the area of brain network plasticity as it pertains to neurorehabilitation, particularly in recovery from stroke. I am trying to apply a two-pronged approach to this difficult problem. First I am using the novel technique of resting-state functional connectivity MRI (fcMRI) to evaluate the overall integrity of distributed brain networks in the acute and chronic phases after stroke. With this approach I hope to identify specific patterns of functional connectivity that are useful prognostic indicators and that may give us insight into the mechanisms of endogenous recovery. Second, I plan to investigate whether activity-based therapies or non-invasive brain stimulation techniques such as transcranial magnetic stimulation can modulate resting state functional connectivity and lead to improved clinical outcomes.