Christina A. Gurnett, MD, PhD
A. Ernest and Jane G. Stein Professor of Developmental Neurology
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Washington University in St. Louis (WU)
Our major research interest is the genetic basis of musculoskeletal diseases affecting children, including clubfoot and scoliosis. We utilize genome wide linkage analysis to identify disease loci in large families, and then employ association analysis to identify genetic susceptibility factors. Animal models of congenital limb anomalies are also being developed based on the discovery of genes involved in human disease. Additional areas of interest are in the genetics of epilepsy, sleepwalking, and multiple sclerosis.