Saint Louis University (SLU)
Since starting my own laboratory, my research focus has been on developing small molecules for several key protein targets centering on cancer and stem cell biology. I have been working independently on the G protein estrogen receptor (GPER) since graduate school and my lab is beginning to develop small molecule libraries targeting the receptor. The main focus for the project is elucidating the binding pocket, and exploiting it to develop treatments for several disease states. Specifically, we are working on cancer models and gallstone disease models to validate the utility of targeting GPER.