James J. Hsieh, MD, PhD

Professor of Medicine

Washington University in St. Louis (WU)

Our laboratory focuses on understanding how Taspase1 and MLL regulate critical biological pathways with a special emphasis on cancer biology. Specifically, we’d like to utilize combined biochemical and genetic approaches to investigate how the evolutionarily conserved protease, Taspase1, and its substrates such as MLL coordinate essential cellular and developmental processes.