Jeffrey R. Millman, PhD

Washington University in St. Louis (WU)

We are interested in developing and studying the differentiation of human pluripotent stem cells to insulin-producing pancreatic beta cells for diabetes cellular therapy and drug screening. We are primarily using tissue engineering approaches to control beta cell/biomaterial interactions to improve this process. Using this strategy, we are generating beta cells from diabetic patients to study the disease and transplanting these cells into diabetic mice.