Kian H. Lim, MD, PhD

Assistant Professor of Medicine

Washington University in St. Louis (WU)

The main research interest of my lab is to understand the relationship and signaling crosstalk between inflammation and cancer. Chronic inflammation is a major predisposing factor for many human cancers. Conversely, cancers are often referred to as “wounds that never heal” due to the pro-inflammatory nature of tumor cells which over time, create a fibrostromal milieu that supports tumor cell survival, promotes invasion, subverts host immunity and protects tumor cells against chemotherapeutics or radiation. Understanding the pro-inflammatory mechanism of tumor cells will facilitate development of therapeutics that can halt or even reverse this process to improve treatment outcome.