Sheng Chih Jin, PhD

Washington University in St. Louis (WU)

My lab is currently focusing on the formation, development, and application of genetic, genomic, and bioinformatic methods to better analyze and integrate exome and genome sequencing, SNP array, RNA-sequencing, epigenomic, metabolomic, and proteomics data. Through the integration of diverse types of transcriptomic and epigenetic functional annotations, the integrative genomic analysis will provide a better understanding of the molecular basis of neurodevelopmental disorders and cardiovascular diseases. Following integrative genomic analyses, we use zebrafish and induced pluripotent stem cell models to precisely model human mutations. Our mission is to provide meaningful and interpretable insight into disease biology and define new targets for risk determination, prevention, and therapy.