Sidharth V. Puram, MD, PhD

Washington University in St. Louis (WU)

My research is primarily focused on cancers of the head and neck, which is also my surgical area of expertise. Our group is interested in understanding aspects of tumor heterogeneity as it pertains to malignant, stromal, and immune cell diversity and in particular understanding the molecular underpinnings that may drive metastasis and treatment resistance. We leverage cutting edge sequencing techniques such as single cell RNA sequencing as well as traditional biochemical and functional approaches to better understand this challenging disease.