Washington University in St. Louis (WU)
My research focuses on understanding the immune microenvironment in glioma, with an emphasis on how innate immune signaling shapes anti-tumor immunity. I am particularly interested in the interactions between myeloid cells and T cells, and how these interactions influence T cell infiltration and function within the brain tumor microenvironment. By integrating single-cell and spatial transcriptomic approaches, my work aims to define the cellular composition and spatial organization that drive tumor progression and therapeutic response. Ultimately, I seek to identify novel immunomodulatory strategies to enhance immunotherapy efficacy for patients with brain tumors.