10. A Pharmacogenetic Algorithm for Days 6-21 of Warfarin Therapy Predicts the Therapeutic Warfarin Dose

Introduction: Warfarin remains a commonly prescribed anticoagulant, use of which is complicated by significant inter-patient variability in the therapeutic dose and a narrow therapeutic index. Algorithms to refine the warfarin dose are needed, especially during days 6-21 of warfarin therapy, when iatrogenic hemorrhages are common.    Objective: To develop clinical and genotype-guided dosing algorithms for days […]