Diabetes reversed in mice with genetically edited stem cells derived from patients (Links to an external site)

Scientific beta cells in mice

Using induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes called Wolfram syndrome, researchers transformed the human stem cells into insulin-producing cells and used the gene-editing tool CRISPR-Cas9 to correct a genetic defect that had caused the syndrome. They then implanted the cells into lab mice […]

Clinical trial launches to evaluate antimalarial drugs for COVID-19 treatment (Links to an external site)

Washington University School of Medicine in St. Louis is launching a clinical trial for patients hospitalized with COVID-19 at Barnes-Jewish Hospital. The trial will investigate the effectiveness of different combinations of the antimalarial drugs chloroquine and hydroxychloroquine and the antibiotic azithromycin in treating ill patients infected with the novel coronavirus.

ICTS Announces 2020-2021 CTRFP Awardees

Washington University Institute of Clinical and Translational Sciences (ICTS) awards 24 investigators with grants as part of the 13th annual Clinical and Translational Research Funding Program (CTRFP). The CTRFP is the largest internal grant funding program of the ICTS. Grant awardees are required to submit projects for funding that promote the translation of scientific discoveries […]

Inaugural Funding Cohort Announced for New Partnership Development and Sustainability Support Program (PDSS)

Linhorst-Xaverius-Clark-Bravo-Wang-Patel-newspost

The Washington University Institute of Clinical and Translational Sciences and Washington University’s Institute for Public Health announce six partnerships selected to receive funding through the new Partnership Development and Sustainability Support (PDSS) program. This funding program provides up to $10,000 to community-academic partnerships for a 12-month period. It enables partners to develop the trust, infrastructure, […]

Building a Learning Health Care System: From Lab to Laptop

For the ICTS, Valentine’s Day was all about the love of informatics. On February 14, the ICTS hosted their third annual Symposium and Poster Session held at the Eric P. Newman Education Center on the campus of Washington University School of Medicine in St. Louis. The day-long event featured presentations, breakout discussions, and a poster […]

KL2 Scholar Utilizes CTSA Resources to Advance MRSA Research

Breakthrough research is rarely accomplished in a vacuum. Years of training, time spent writing and countless hours coordinating resources is an inherent part of any researcher’s work on the path to a successful study. Such is the case for Stephanie Fritz, MD, MSCI, ICTS member and senior author of a new study on how the […]

Investigator and Bioethics Expert James DuBois Weighs In on the Ethical and Practical Barriers to Qualitative Data Sharing

James DuBois, DSc, PhD

Qualitative data—such as data from interview or focus group studies—has a unique value in understanding health behaviors and traits. It is often used to understand attitudes and preferences, as well as complex and hidden behaviors. Qualitative research has led to deeper understandings of risk factors for HIV, teen pregnancy, and illegal drug use. When participants […]