Washington University in St. Louis (WU)
Dr. Sheikh specializes in bacterial pathogenesis, host-pathogen interactions, host responses, and vaccines, with a special focus on enteric bacterial pathogens including enterotoxigenic E. coli (ETEC). His research focuses on understanding the effects of enteric infections on intestinal cells leading to long-term consequences including enteropathic changes leading to malnutrition in children. To study the effects of enteric infections on intestinal stem cells and gut enteropathy he uses organoid system, mouse model, single-cell sequencing, flowcytometry, CRISPR/Cas genome editing, and other genomic and proteomic tools.