University of Missouri – Columbia (MU)
Brain stimulation using implanted devices has revolutionized the treatment of functional disorders including movement disorders and epilepsy. However, the precise mechanisms by which neurostimulation acts on the brain and modulates pathologic circuits is an area of intense research. My lab focuses on studying the mechanisms by which brain stimulation affects large-scale brain networks with the goal of improving the treatment of network disorders, particularly with respect to memory deficits. We address this through a two-pronged approach: 1) characterizing how stimulation parameters influence whole-brain network connectivity in normal and diseased brains and 2) identifying the electrophysiologic bases of memory performance so that decrements in performance may be modulated with brain stimulation.