George P. Souroullas, PhD
- Email: email@example.com
Washington University in St. Louis (WU)
The overarching research interest of the Souroullas lab is the role of epigenetic mechanisms during cancer development. The identification of mutations in epigenetic and chromatin factors in cancer, along with the reversible nature of their function, present us with an incredible opportunity in translational medicine. Understanding the phenotypic and molecular consequences of epigenetic dysregulation during carcinogenesis and the interplay between genetic and epigenetic aberrations remains a challenge, but it is critical in developing more effective therapeutic strategies. My lab combines the use of genetically engineered murine models with epigenetic, molecular, biochemical, and pharmacological methods to study how mutations in epigenetic factors promote the development of lymphoma and melanoma.