Washington University in St. Louis (WU)
Dr. Osborne’s (he/him) research is focused on identifying the neural mechanisms and processes that underlie the risk for developing psychotic disorders. The ultimate goal of his research is to improve early identification of those at greatest risk and inform early interventions to reduce illness progression and optimize recovery. To achieve this goal, he uses multiple methods (e.g., behavioral, EEG, neuroimaging) with prospective longitudinal research designs to examine distinct, but mechanistically related, risk factors in individuals across the psychosis spectrum, such as substance use (i.e., cannabis) and socio-affective deficits. A major area of his research examines how motor system abnormalities, particularly abnormalities in the cerebellum and its relays, contribute to the progression and onset of psychosis symptoms.