Malay Choudhury, PhD

Washington University in St. Louis (WU)

Our current research focuses on delineating the cellular, molecular, and metabolic processes involved in the development of fibrotic disorders such as Idiopathic pulmonary fibrosis (IPF). We are currently dissecting how metabolic networks may provide disease and context-specific targets for selective interruption of pathological cellular functions, and how these metabolic adaptations may in turn be targeted therapeutically for IPF (and by extension, other fibrogenic disorders). We have demonstrated a compelling vision for merging the worlds of cell signaling and metabolism to understand targetable mechanisms driving fibroblast function and fibrosis. The ultimate goal of our research is to identify new disease targets and developing novel therapeutic approaches to treat chronic lung diseases.