Matthew J. Silva, PhD

Washington University in St. Louis (WU)

The Silva lab studies bone. We are focused on two main questions. 1) How does mechanical loading (e.g., weight-bearing exercise) stimulate bone formation and increase bone mass? 2) How do bones heal after injury (e.g., stress fracture and full fracture)? By studying how the skeleton responds to mechanical stimulation and how it heals after injury, we aim to contribute to the discovery of new approaches to treat reduced bone mass and strength in aging/osteoporosis, and to enhance bone repair in patients who suffer from non-healing fractures.