Rajeev Aurora, PhD
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Saint Louis University (SLU)
The focus of our research is on how estrogen (E2) and aging affects the immune system. Both E2-loss and aging promote chronic inflammation which underlies the etiology of several diseases of aging. Our laboratory has recently determined a novel pathway that promotes chronic inflammation upon E2 loss. Aging promotes chronic inflammation by a number of mechanisms. Our current focus is to understand and reveal these mechanisms and how they promote tissue-specific pathology.