Sharon Cresci, MD

Associate Professor of Medicine

Washington University in St. Louis (WU)

My laboratory is engaged in translational research focused on investigating genetic and pharmacogenetic associations with cardiovascular disease, with a particular interest in diabetic cardiovascular disease. Ongoing projects in my laboratory include 1) comprehensively investigating the genetic and pharmacogenetic associations of PPAR-pathway variants, using a custom PPAR-pathway targeted-genotyping 3K array, in a population with type 2 DM and coronary artery disease that has been extensively phenotyped (BARI 2D cohort); 2) assessing the predictive impact of genetic variants in the context of modern post-ACS therapy in a cohort of 4,500 patients with acute myocardial infarction (TRIUMPH cohort).