ICTS investigator advances research into noise-induced hearing loss

Mark Rutherford, PhD

Humans evolved in a relatively quiet landscape, without natural selection for protection from acoustic trauma. In today’s increasingly loud industrialized world, exposure to noise affects us all, and life is only getting louder. According to findings from the 2011-2012 National Health and Nutrition Examination Survey (NHANES), nearly one in four of US adults aged 20-69 years […]

ICTS Core Provides Foundation for Unprecedented Pediatric COVID Collaboration

The Washington University Pediatric and Adolescent Research Consortium (WU PAARC), a practice-based research network of community pediatric healthcare providers, has been an integral part of the ICTS since the inception of the CTSA program at Washington University in 2007. As a core of the ICTS and a part of the Integrating Special Populations function, WU […]

Investigator uses ICTS resources for COVID-19 research and clinical trial efforts

Rachel Presti, MD, PhD

The CTSA program was developed to accelerate new treatments from the lab to patients, enabled to a large extent by patients participating in and benefiting from clinical trials. Clinical trials provide that needed bridge from human subjects to hypotheses to treatments that can directly benefit human health. And, never has this connection been more critical […]

Measuring the impact of science; How CTSAs use the Translational Science Benefits Model to show real world benefits

Challenge of measuring impact Government, non-profits, and organizations fund research with the ultimate goal of improving health and society. Yet measuring these long-term outcomes can be challenging, and research impact has traditionally been tied to quantitative productivity, like bibliometrics and grant funding, and not necessarily the broader impacts of research. For years, researchers lacked a […]

If you build it, will they come? Linking researcher engagement and scientific productivity in large infrastructure grants

As it turns out, they will. A team of researchers that has been evaluating the Washington University Institute for Clinical and Translational Sciences (ICTS) since 2010 has released new findings. They suggest that CTSA member researchers who engaged with dedicated ICTS infrastructure and resources increased their research productivity; members who took advantage of ICTS services […]

Engaging special populations with community and investigator partnerships; ICTS provides framework for unique collaboration to develop and thrive

Christine Berg, PhD, OTR/L, FAOTA, (left) and Rev. Dr. Paulette Sankofa (right)

A Relationship Begins One could say she has community in her heart. Rev. Dr. Paulette Sankofa, EdD, grew up in the St. Louis West End and remembers the tight community connections, particularly among older adults that was commonplace at that time. It is this sense of community and respect for seniors instilled as a young […]

Saint Louis University ICTS investigator utilizes funding mechanism to advance research on opioid therapy options

Daniela Salvemini, PhD

Neuropathic pain affects millions of Americans every year. This fact combined with the nationwide crisis of opioid misuse reinforces the need for safer and more effective therapies to help those suffering from chronic pain. In tandem with efforts from the National Center for Advancing Translational Sciences and in an effort to advance research in this […]

ICTS investigators test fluvoxamine repurposed as treatment for COVID, Utilize fully-remote clinical trial to reach participants

The proverbial saying ‘Necessity is the mother of invention’ is frequently used to explain how great innovations are made during times of urgent need. Never has the need been direr than when the COVID pandemic hit in March 2020 and health care providers were struggling to find treatments for patients fighting this new and deadly […]

KL2 Alumnus Maximizes ICTS Options to Gain Skills for Dual Career as Researcher and ICU Clinician

In 2015 Kenneth Remy, MD, MHSc arrived in St. Louis to join the Washington University School of Medicine faculty as an assistant professor of pediatrics and launched his lab studying the intersection of transfusion hematology and immune dysregulation. He was fresh off a National Institutes of Health (NIH) fellowship in Bethesda, Maryland, gaining experience that […]