Next-gen Alzheimer’s drugs extend independent living by months (Links to an external site)

An Alzheimer’s patient with very mild symptoms who undergoes treatment with one of the new, next-generation therapies could expect to gain eight or 10 months living independently, according to a study by researchers at WashU Medicine. The new analysis interprets the benefits of the drugs in a way that is meaningful to patients and families, to help them make informed decisions about treatment.

In the past two years, the Food and Drug Administration has approved two novel Alzheimer’s therapies, based on data from clinical trials showing that both drugs slowed the progression of the disease. But while the approvals of lecanemab and donanemab, both antibody therapies that clear plaque-causing amyloid proteins from the brain, were greeted with enthusiasm […]

ICTS Precision Health supports research on new genetic cause of neurodevelopmental disorders’

Christina Gurnett, MD, PhD

Christina A. Gurnett, MD, PhD, A. Ernest and Jane G. Stein Professor of NeurologyHead, Division of Pediatric and Developmental Neurology Chief of Neurology, St. Louis Children’s Hospital, was recently published in the American Journal of Human Genetics. A cross-disciplinary team of researchers and physicians from Children’s National Hospital and WashU Medicine, in collaboration with physicians […]

WashU Investigator utilizes and nurtures community-based relationships to propel research and serve local communities

For investigators, there is much to be considered when choosing how to conduct research projects. Which demographics will you target? Which funding mechanisms should you apply for? How long will it take you to accomplish your aims? One of the most important considerations that seems simple enough, though it can sometimes appear unfamiliar to investigators, […]

Leadership Changes to ICTS Research Development Program

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The ICTS extends its gratitude to Betsy Keath, PhD, for twelve years of exceptional service to the ICTS and Washington University. Dr. Keath, Associate Professor of Medicine, has served as the ICTS Translational Research Navigator and Director of the Research Development Program (RDP). We offer our heartfelt congratulations to Dr. Keath as she embarks upon her […]

National Institutes for Health Awards PRIDE Grant (Links to an external site)

(L-R) Drs. Arbeláez, Brookheart, Reeds

Postbaccalaureate Research Education Program in Diabetes, Endocrinology, and Metabolic Diseases Grant  Ana Maria Arbeláez, MD; Rita Brookheart, PhD; and Dominic Reeds, MD, WashU Medicine clinician–researchers and directors, were recently the recipients of one of three National Institutes for Health Grants. This grant offers funding for the Postbaccalaureate Research Education Program in Diabetes, Endocrinology, and Metabolic Diseases (PRIDE) […]

Development of a metabolome-based respiratory infection prognostic during COVID-19 arrival (Links to an external site)

Jeffrey P. Henderson, MD, PhD, FIDSA

Jeffrey P. Henderson, MD, PhD, FIDSA, Professor of Medicine and Molecular Microbiology, at WashU Division of Infectious Diseases, was recently published in ASM Journals with new insights into the development of a metabolome-based respiratory infection prognostic during COVID-19. Henderson highlights that the supportive environment at WashU Medicine played a crucial role in making this work possible, an aspect that is […]

Former TL1 postdoc scholar, Ronald Fowle-Grider, PhD makes strides in fructose-related cancer research (Links to an external site)

Ronald Fowle-Grider, PhD

Former TL1 postdoctoral scholar Ronald Fowle-Grider, PhD cites support of the program in ground breaking research “Dietary fructose enhances tumour growth indirectly via interorgan lipid transfer”. His findings were recognized by WashU’s The Source, which featured an overview of the discoveries. The full research publication is available in the journal Nature.

Sean Smith, MD, MPHS published in Wiley Online Library

Sean Smith

Congratulations to Sean Smith, MD, MPHS (Neurology) on his recent publication on a progressive treatment for Amyotrophic Lateral Sclerosis (ALS). A specific subset of patients taking Tofersen have shown slowing of disease progression, and disease stabilization with recovery of function in some patients. PROUD-MED extends a heartfelt Congratulations and wishes Dr. Smith the best in […]

Jonathan Williams, MD receives AAN Project Grant

Congratulations to PROUD-MED Scholar Jonathan Williams, MD (Neurology) on his recent American Academy of Neurology (AAN) Diversity, Equity, and Inclusion (DEI) Project Grant funded by the AAN for 2025. The AAN DEI Innovator Grants and AAN DEI Project Grants support projects, events, and activities that foster DEI within the WashU Medicine Department of Neurology and the communities they serve. Dr. […]

New drug tested to reduce side effect of ‘half-matched’ stem cell transplants (Links to an external site)

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Clinical trial indicates safety, fewer cases of life-threatening graft-versus-host disease than expected Adding a new drug to standard care for stem cell transplant recipients may reduce a life-threatening side effect, according to an early-stage clinical trial conducted at Washington University School of Medicine in St. Louis. The trial showed that patients being treated for various […]