Introduction: Ultrasound (US) guided confirmation of central venous catheters (CVC) has similar sensitivity to the traditional chest x-ray (CXR), while being less resource intensive and lowering labor cost. In spite of this data, clinicians continue to obtain CXR for CVC confirmation and have not adopted US, a new innovation, to replace CXR. A protocol was […]
Introduction: Every year national funding organizations invest billions of dollars in the development and evaluation of interventions to improve people’s wellbeing. Pragmatic randomized controlled trials can generate robust evidence in support of one treatment over others. However, even where such evidence is generated, practice may not change. Based on findings published in the late 20th […]
Introduction: The Greater Plains Collaborative (GPC) and PCORnet Clinical Data Research Networks capture healthcare use within their health systems but may lack information on care received elsewhere in the community. Here, we describe are usable environment (GPC Reusable Observable Unified Study Environment [GROUSE]) that integrates hospital and electronic health records data in the PCORnet common […]
Introduction: Multiple myeloma (MM) is a common hematologic malignancy. Our studies utilized electronic health record (EHR) data in the nationwide Veteran Health Administration to study the risk of progression of monoclonal gammopathy of undetermined significance (MGUS) to MM. Disease confirmation is crucial in these studies. Relying on manual laboratory (lab) data abstraction to confirm diagnoses […]
Introduction: In 2020, suicide was the 12th leading cause of death for people of all ages in the United States (US), the second leading cause of death for people, aged 10 to 34, and the fifth leading cause of death for people aged 35 to 54 (Garnett et al., 2020). Despite prevention and treatment efforts, […]