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Test is faster, simpler than nasal, oral swab tests and enables screening on a massive scale

This episode of ‘Show Me the Science’ looks at where the nation has come and where we may be headed as coronavirus infections and deaths continue to rise

The Translational Science Benefits Model (TSBM), created by the Institute of Clinical and Translational Sciences at Washington University in St. Louis, is a framework public health and clinical scientists use to demonstrate the impact of their work in the real world. First published September 8, 2017 in Clinical and Translational Science, TSBM was inspired by the desire to […]

Brain tumors are typically diagnosed using MRI imaging because taking a sample for a tissue biopsy is risky and may not be possible due to tumor location or a patient’s poor health conditions. Researchers at Washington University in St. Louis are developing a method to diagnose brain tumors without any incisions.

Washington University in St. Louis, the St. Louis County Department of Public Health and other collaborators are conducting a survey of St. Louis County residents and offering COVID-19 testing to gauge the prevalence of and risk factors for the illness.

As the COVID-19 pandemic continues to claim lives around the world, much research has focused on the immune system’s role in patients who become seriously ill. A popular theory has it that the immune system gets so revved up fighting the virus that, after several days, it produces a so-called cytokine storm that results in […]

As U.S. scientists ramp up a national effort to evaluate COVID-19 vaccine candidates at clinical trial sites across the country, researchers at Washington University School of Medicine in St. Louis and the Saint Louis University Center for Vaccine Development have been tapped to join the historic effort to find a COVID-19 vaccine that can prevent […]

Researchers can submit potential antiviral molecules for screening Six months into the pandemic, people diagnosed with mild cases of COVID-19 still are told to isolate themselves and wait out the infection at home. Doctors monitor such patients so they can intervene if their condition deteriorates, but no antiviral drugs have been shown to hasten recovery […]

In collaboration with The Foundation for Barnes-Jewish Hospital (FBJH), the Washington University Institute of Clinical and Translational Sciences (ICTS) awards 11 investigators as part of the COVID-19 Research Funding Program. These eight-month grants provide critical financial support for COVID-19 translational research with potential direct clinical impact within the next 12 months. All research will be […]

Back in mid-March at the forefront of the pandemic shutdown, Washington University School of Medicine neurologist and ICTS investigator Eric Landsness, MD, PhD, was immediately thinking about how he could help. “As an academic neurologist, I wasn’t on the front lines,” commented Landsness. “But it was personally important to me to find a way that […]

The National Institutes of Health has launched a centralized, secure enclave to store and study vast amounts of medical record data from people diagnosed with coronavirus disease across the country. It is part of an effort, called the National COVID Cohort Collaborative (N3C), to help scientists analyze these data to understand the disease and develop treatments. […]

Such antibody tests use finger-prick blood samples, deliver quick results

Providing such patients oral meds reduces hospital readmissions

Biorepository project initiated early in pandemic to streamline coronavirus research efforts

Provides ICTS Investigator Valuable Opportunity for Professional Development The CTSA program provides opportunities for hub members to come together and advance knowledge and progress around various topics. One way this is accomplished is through working groups. Working groups consider and develop solutions around a specific clinical and translational science issue and provide deliverables that fill […]

To help unravel the mysteries of COVID-19, scientists are sequencing the DNA of young, healthy adults and children who develop severe illness despite having no underlying medical problems. The researchers are looking for genetic defects that could put certain individuals at high risk of becoming severely ill from the novel coronavirus.

Planning for your first R01 application can be daunting. Even for seasoned investigators, it takes time and requires sufficient preparation. Early-stage investigators can find needed support by utilizing resources from the ICTS throughout their grant submission process. Recently funded by the National Institute on Aging with the National Institutes of Health (NIH), ICTS members, Sarah […]

High levels of social distancing would lower the COVID-19 infection, hospitalization and death rates over the next six months across all counties in Missouri, finds a new study from Washington University in St. Louis.

The community-academic partnership between Saint Louis University researcher Pamela Xaverius, PhD, MBA, Associate Professor of Epidemiology, Saint Louis University College for Public Health and Social Justice and Rose Anderson-Rice, Deputy Director with Generate Health, is utilizing ICTS funding to meet the needs of mothers and families living in government housing during the current COVID-19 pandemic.  […]

Medical professionals dramatically shift focus to help patients infected with coronavirus.

Using induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes called Wolfram syndrome, researchers transformed the human stem cells into insulin-producing cells and used the gene-editing tool CRISPR-Cas9 to correct a genetic defect that had caused the syndrome. They then implanted the cells into lab mice […]

Infectious diseases physicians at Washington University School of Medicine in St. Louis have developed an expanded access program to give blood plasma from COVID-19 survivors to critically ill patients at Barnes-Jewish Hospital in St. Louis.

The Brown School’s Jason Purnell will lead a response team of over 40 St. Louis area nonprofits, social service agencies and governments to deal with the coronavirus pandemic.

Washington University School of Medicine in St. Louis is launching a clinical trial for patients hospitalized with COVID-19 at Barnes-Jewish Hospital. The trial will investigate the effectiveness of different combinations of the antimalarial drugs chloroquine and hydroxychloroquine and the antibiotic azithromycin in treating ill patients infected with the novel coronavirus.

Washington University Institute of Clinical and Translational Sciences (ICTS) awards 24 investigators with grants as part of the 13th annual Clinical and Translational Research Funding Program (CTRFP). The CTRFP is the largest internal grant funding program of the ICTS. Grant awardees are required to submit projects for funding that promote the translation of scientific discoveries […]