Introduction: Millions of indwelling catheters are placed each year to monitor urine output. Catheter associated urinary tract infections (CAUTIs) are the most commonly hospital-acquired infections and associated with urinary catheters. Previous efforts to decrease CAUTIs in the intensive care unit (ICUs), which are more likely to use urinary catheters, have had minimal success. Despite unclear […]
Introduction: Fatty acid translocase CD36 regulates cardiac function, and its deletion in rodents associates with atrioventricular block and bradycardia and increasing risk of sudden death following prolonged fasting. Preclinical and clinical research show that monocyte chemotactic protein-1/chemokine (C-C motif) receptor 2 (MCP-1/CCR2) regulates myocardial remodeling and inflammation during cardiac disease. Our preliminary data, conducted with […]
Introduction: Performing self-care and domestic life tasks are key measures of functional independence for older adults. While both depression and anxiety symptoms have been correlated with increased functional limitation, these two disorders are most often studied separately, despite frequent co-occurrence and plausible interactive effects. This study examined the impact of comorbid depressive and anxiety symptoms […]
Introduction: Chronic hypertension (CHTN), gestational hypertension (GHTN), preeclampsia (PE), and CHTN with superimposed PE (siPE) are hypertensive disorders of pregnancy (HDP). Criteria distinguishing HDPs are imprecise and the factors driving development of one or more HDPs and progression to PE, associated with increased risk of maternal and fetal morbidity and mortality, are unclear. Identifying more […]
Introduction: Current treatments for Tourette Syndrome (TS) and other chronic tic disorders (CTD) are inadequate, and patients desire new treatment options. Median nerve stimulation (MNS) at 10-12 Hz was recently proposed as a novel treatment for TS/CTD. We report on 31 people ages 15-64 with TS/CTD who participated in an open-label, comparative (within-group, several time […]
Introduction: Food insecurity (FI), characterized by limited or uncertain access to adequate food, has been associated with eating disorders (EDs). This study explored whether FI was associated with ED behaviors, ED diagnosis, current treatment status, and treatment-seeking intentions among adults who screened positive for probable EDs on an online ED screen. Methods: Respondents with probable […]
Introduction: Atrial fibrillation (AFib) is the most common irregularity of heartbeats. It can cause significant symptoms and impair heart function. Its irregular and often very rapid heart rhythm can lead to blood clots that cause stroke or heart attack, especially as the patient ages. The irregularity of heartbeats has prevented visualization of the heart using […]
Introduction: Assessment of comorbidities is essential to clinical research and predicts adverse events and death. Prescription medications could be a tool for predicting risk independent of the Charlson Comorbidity Index (CCI). Additionally, clinicians have access to prescription medication lists, facilitating assessment of comorbidities. Methods: Retrospective study conducted of US Veterans treated for metastatic castrate resistant […]
Introduction: Medication hoarding is an important health risk factor (Sorenson et al., 2005). In addition, hoarding is related to falls and injuries (Wick & Zanni, 2011) and may be particularly concerning in a community-dwelling older population (Dozier, Porter, & Ayers, 2016). Individuals with complex medication regimens who require assistance from family caregivers may be at […]
Introduction: Many studies have shown that the progression of Alzheimer’s disease (AD) varies substantially from patient to patient. It is important to identify subpopulations who may benefit from the investigational treatment. Subgroup identification can help clinicians select patients who are most likely to have a positive response to a treatment. It may also inform the […]